February 12, 2024
- A new research article has examined the effects of lead (Pb) exposure on the immune system and gene expression in the brains of BTBR mice, which are bred to display autism-like traits. Using flow cytometry and RT-PCR techniques, the authors found that Pb exposure increased the population of certain immune cells and altered the expression of genes associated with immune response in these mice. Specifically, Pb exposure led to increased levels of inflammatory markers and decreased levels of regulatory markers, indicating immune dysfunction. These findings suggest that Pb exposure may worsen immune system dysfunctions linked to ASD and potentially increase the risk of ASD development.
- A team of Ohio State University researchers has revealed that adults with autism spectrum disorder experience elevated rates of many physical and mental health conditions compared to adults in the general population. Their findings indicate that individuals on the spectrum are more likely to suffer from anxiety disorders (55%), mood disorders (43%), attention deficit hyperactivity disorders (34%), epilepsy (12%), heart disease (16%), gastrointestinal conditions (19%) and obesity (17.1%). Interestingly, the study found lower rates of asthma (9%) and sleep disorders (3%) among adults with ASD compared to adults without the disorder.
- A new study has assessed the prevalence and associations of autistic traits in adults diagnosed with Social Anxiety Disorder (SAD) and compared those traits to healthy controls (HC). Results showed that the SAD group scored significantly higher in all Adult Autism Subthreshold Spectrum (AdAS Spectrum) and Social Anxiety Spectrum – Short Version (SHY-SV) questionnaire domains and total scores than the HC group, with strong positive correlations found between SHY-SV and AdAS Spectrum scores. Additionally, AdAS Spectrum scores, particularly in childhood/adolescence, non-verbal communication, empathy, and restricted interests and rumination domains, predicted higher SHY-SV scores. These findings reinforce the association between SAD and autistic traits in adults, highlighting the significant overlap in core features and the predictive role of autistic traits in SAD symptom severity.
- The Autism Research Institute and the World Autism Organization have released a webinar titled “Examing the Transition to Adulthood in Autism: Challenges and Opportunities in the Aim of Thriving.” This free webinar explores the transition to adulthood and its implications for individuals with autism. The presentation focuses on the ecosystem mentality and discusses recent findings supporting a holistic and future-oriented integrated care system for adults on the spectrum. It also details potential areas of capacity building within post-secondary education and employment and highlights the need for cross-sector collaboration and lifelong care.
