April 22, 2024
- Recent Ukrainian research reveals that children with ASD associated with genetic folate cycle deficiency (GFCD) show a distinct microbial profile characterized by a high microbial load in their gastrointestinal tract dominated by opportunistic microorganisms. This profile differs significantly from healthy children of the same age. The ASD and GFCD-affected children’s most frequently detected infectious agents include TTV, HHV-7, HHV-6, EBV, Streptococcus Pyogenes, and Candida albicans. The study suggests that the abnormal microbial profile in children with ASD could be linked to compromised immune responses and specific immune deficiencies, such as natural killer cell dysfunction. These findings emphasize the need for further research to explore the microbial factors influencing the development and severity of ASD and related neuropsychiatric syndromes. They also could pave the way for targeted therapeutic interventions.
- A new research letter by scientists from the Kennedy Krieger Institute reveals alarming rates of suicidal thoughts among children with autism. A survey of 968 caregivers of children with autism aged 8 to 17 found that over 40% reported their child wanting to die. The findings were even more concerning for younger children aged 8 and under, with 36.2% expressing a desire to die, 35.3% wishing to end their lives, and 18.1% having a suicide plan. These rates are notably higher than in neurotypical children of the same age. The research letter, published in JAMA Pediatrics, underscores the lack of validated suicide risk screening tools and interventions for this vulnerable age group. The authors emphasize the importance of regular mental health check-ins for these children and urge parents to be vigilant about any signs of distress, as not all at-risk children display warning signs commonly associated with suicide.
- The Autism Impact Fund (AIF) has successfully closed its inaugural fund, raising $60 million to support innovative diagnostics and treatments for autism, neurodevelopmental disorders, and other chronic conditions. Founded in 2021 by Chris Male after his son’s autism diagnosis, AIF initially attracted high-net-worth families dissatisfied with the slow pace of autism innovation. The fund has since expanded its investor base to include family offices and larger institutions. AIF aims to continue investing in groundbreaking solutions, with half of the fund already deployed across 12 portfolio companies, including Cortica, SpectrumAi, and BioROSA.
- The Documenting Hope Conference is scheduled for November 15-17 at the Omni ChampionsGate in Orlando, Florida. This year’s Adventures in Healing conference offers the “ultimate field guide to restoring health in our children.” Registration is open to parents, healthcare professionals, nutritionists, SLPs, OTs, social workers and other professionals.
